Infertility Caused by Unexplained Infertility Problems






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1. What Is Unexplained Infertility?

Unexplained infertility is infertility that has no obvious cause. It is the most frequent infertility diagnosis given to women. Close to 30% of all female fertility cases will end up being diagnosed as unexplained infertility.


For a woman to be diagnosed with unexplained infertility, she and her partner will have already gone through a fertility work up and no real explainable cause can be found for the fertility issues. It’s important to remember that while doctors can test for many different causes of infertility, not every single cause can be pinpointed.

2. What Is NOT Unexplained Infertility?

It is very important that before a diagnosis of unexplained infertility is given, that a couple goes through extensive fertility testing. Unexplained infertility is not endometriosis or tubal disease.

It’s not low sperm counts or poor sperm motility. If a couple is diagnosed with unexplained infertility, the hormones must be able to be developed and released properly.


The eggs must also be of good quality, and they must be able to develop and mature properly. The egg must be released properly and be able to travel down the Fallopian tubes.

The sperm must be of good quality and be able to swim properly. These are just a few of the tests that have to occur before a couple can be diagnosed with unexplained infertility.

3. Age And Unexplained Infertility

One very interesting tidbit is that there is a greater instance of unexplained infertility when it comes to increased maternal age. Diagnosis of unexplained fertility is much more common in women over 35, and extremely common in women over 38 years of age.


This is because there are much more issues and problems that can occur in older women that can lead to unexplained infertility. Women who are older than 35 should talk to their doctor about getting pregnant with unexplained infertility, since there are sometimes issues there that might be more complicated.

4. More About Unexplained Infertility

It is very hard to diagnose every single cause of infertility. There are so many different things that can lead to and contribute to infertility, unexplained infertility is just naturally sometimes a common diagnosis when things are not able to be figured out completely. Doctors usually like to try common treatment options like Clomid or other medications in order to try to jumpstart ovulation.


Many times, these medications are successful in jumpstarting ovulation even when doctors are not sure what is wrong. If medications do not work to jumpstart ovulation in women with unexplained infertility, sometimes IVF may be used or alternative treatment options.

Dr. Karen Leham, MD

Dr. Karen Leham is double board-certified in Obstetrics and Gynecology and in Reproductive Endocronology and Infertility. Dr. Leham completed her residency at Loyola University, followed by a fellowship at UCLA.